Peptic Ulcer Causes: What Really Triggers Stomach Sores

When dealing with Peptic ulcer causes, the factors that lead to painful sores in the stomach or duodenum, often tied to acid damage and bacterial infection. Also known as stomach ulcer triggers, it covers a mix of infections, medicines, and habits that erode the gut lining, the picture becomes clearer once we break down the main players. Helicobacter pylori, a spiral‑shaped bacterium that colonizes the gastric mucosa and weakens its protective mucus tops the list – about half of all ulcer cases start here. NSAIDs, non‑steroidal anti‑inflammatory drugs such as ibuprofen or naproxen that inhibit prostaglandin production are the second biggest culprit because they strip away the stomach’s natural defenses. Together they form a classic semantic triple: peptic ulcer causes include H. pylori infection and NSAID use, and both disrupt the mucosal barrier, allowing acid to bite into tissue.

Key Lifestyle and Physiological Triggers

Beyond microbes and meds, everyday habits shape ulcer risk. Chronic stress doesn’t directly create a sore, but it ramps up stomach‑acid secretion and slows healing, making the lining more vulnerable – a clear cause‑effect link. Smoking adds another layer by reducing bicarbonate production and impairing blood flow, which hampers the mucosa’s repair mechanisms. Heavy alcohol use irritates the stomach lining and can worsen H. pylori infection, creating a feedback loop where each factor amplifies the other. Even dietary patterns matter; while spicy foods don’t cause ulcers on their own, a diet low in fiber and high in processed items can increase gastric acidity and delay recovery. These connections form several semantic triples: stress can exacerbate ulcer formation, smoking influences ulcer risk, and alcohol consumption interacts with bacterial infection.

Understanding these peptic ulcer causes helps you spot the real threats before they turn into pain. Below you’ll find a curated set of articles that dive deeper into each factor – from how to test for H. pylori and safely stop NSAIDs, to practical tips for cutting stress, quitting smoking, and adjusting your diet. Whether you’re looking for medical explanations or everyday lifestyle fixes, the collection gives you the tools to prevent or manage ulcers effectively.

Stress and Stomach Ulcers: How Stress Triggers Ulcers
Morgan Spalding 1 October 2025

Stress and Stomach Ulcers: How Stress Triggers Ulcers

Explore how chronic stress interacts with stomach ulcers, the science behind cortisol and acid, and practical steps to prevent ulcers through stress management.