In recent years, there has been growing interest in the long-term safety of Alendronate, a medication commonly used to treat osteoporosis. Research suggests that while Alendronate is generally well-tolerated and effective in increasing bone density, some concerns remain. Notable side effects include gastrointestinal issues and the rare but serious risk of atypical femur fractures. Despite these concerns, most studies indicate that the benefits of Alendronate use outweigh the risks for most patients. However, it's essential for individuals to consult with their healthcare providers to determine the best course of treatment for their specific needs.